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Pravastatin Improves Function in Hibernating Myocardium by Mobilizing CD133+ and cKit+ Bone Marrow Progenitor Cells and Promoting Myocytes to Reenter the Growth Phase of the Cardiac Cell Cycle

HMG-CoA reductase inhibitors have been reported to increase circulating bone marrow progenitor cells (BMPCs) and variably improve global function in heart failure. The potential role of improved perfusion vs. direct effects of statins on cardiac myocytes has not been established. We chronically inst...

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Autores principales: Suzuki, Gen, Iyer, Vijay, Cimato, Thomas, Canty, John M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666151/
https://ncbi.nlm.nih.gov/pubmed/19096024
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.108.188730
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