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A KCNQ channel opener for experimental neonatal seizures and status epilepticus

OBJECTIVE: Neonatal seizures occur frequently, are often refractory to anticonvulsants, and are associated with considerable morbidity and mortality. Genetic and electrophysiological evidence indicates that KCNQ voltage-gated potassium channels are critical regulators of neonatal brain excitability....

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Main Authors: Raol, YogendraSinh H., Lapides, David A., Keating, Jeffery, Brooks-Kayal, Amy R., Cooper, Edward C.
Format: Artigo
Jezik:Inglês
Izdano: 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2666110/
https://ncbi.nlm.nih.gov/pubmed/19334075
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.21593
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