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Tdp1 protects against oxidative DNA damage in non-dividing fission yeast
In humans, a mutation in the tyrosyl-DNA phosphodiesterase (Tdp1) is responsible for the recessively inherited syndrome spinocerebellar ataxia with axonal neuropathy (SCAN1). Tdp1 is a well-conserved DNA repair enzyme, which processes modified 3′ phospho-DNA adducts in vitro. Here, we report that in...
שמור ב:
| Main Authors: | , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
Nature Publishing Group
2009
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2666031/ https://ncbi.nlm.nih.gov/pubmed/19197239 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/emboj.2009.9 |
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