The transcription factor c-Myc enhances KIR gene transcription through direct binding to an upstream distal promoter element

The killer cell immunoglobulin-like receptor (KIR) repertoire of natural killer (NK) cells determines their ability to detect infected or transformed target cells. Although epigenetic mechanisms play a role in KIR gene expression, work in the mouse suggests that other regulatory elements may be invo...

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Bibliographic Details
Main Authors: Cichocki, Frank, Hanson, Rebecca J., Lenvik, Todd, Pitt, Michelle, McCullar, Valarie, Li, Hongchuan, Anderson, Stephen K., Miller, Jeffrey S.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2009
Subjects:
Immunobiology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665893/
https://ncbi.nlm.nih.gov/pubmed/18987359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-07-166389
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