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The adiponectin receptors AdipoR1 and AdipoR2 activate ERK1/2 through a Src/Ras-dependent pathway and stimulate cell growth

Adiponectin is an adipocyte-derived cytokine that has attracted much attention because of its insulin-sensitizing effects in liver and skeletal muscle. Two adiponectin receptors, AdipoR1 and AdipoR2, have been cloned, but relatively little is known about their intracellular signaling mechanisms. We...

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Detalhes bibliográficos
Main Authors: Lee, Mi-Hye, Klein, Richard L., El-Shewy, Hesham M., Luttrell, Deirdre K., Luttrell, Louis M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665882/
https://ncbi.nlm.nih.gov/pubmed/18842004
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi801451f
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