High Resolution Melting Analysis for JAK2 Exon 14 and Exon 12 Mutations: A Diagnostic Tool for Myeloproliferative Neoplasms

JAK2 mutations are important criteria for the diagnosis of Philadelphia chromosome-negative myeloproliferative neoplasms. We aimed to assess JAK2 exon 14 and exon 12 mutations by high-resolution melting (HRM) analysis, which allows variation screening. The exon 14 analysis included 163 patients with...

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Detalhes bibliográficos
Main Authors: Rapado, Inmaculada, Grande, Silvia, Albizua, Enriqueta, Ayala, Rosa, Hernández, José-Angel, Gallardo, Miguel, Gilsanz, Florinda, Martinez-Lopez, Joaquin
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Investigative Pathology 2009
Assuntos:
Regular Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665865/
https://ncbi.nlm.nih.gov/pubmed/19225136
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/jmoldx.2009.080110
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