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Tat-Induced FOXO3a Is a Key Mediator of Apoptosis in HIV-1-Infected Human CD4(+) T Lymphocytes
The high mutation rate of HIV is linked to the generation of viruses expressing proteins with altered function whose impact on disease progression is unknown. We investigated how HIV-1 viruses lacking Env, Vpr, and Nef affect CD4(+) T cell survival. We found that in the absence of these proteins, HI...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2665797/ https://ncbi.nlm.nih.gov/pubmed/19050264 |
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