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HapMap methylation-associated SNPs, markers of germline DNA methylation, positively correlate with regional levels of human meiotic recombination

Inter-individual and regional variability in recombination rates cannot be fully explained by the DNA sequence itself. Epigenetic mechanisms might be one additional factor affecting recombination. A biochemical approach to studying human germline methylation is difficult. We used the density of the...

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Detalles Bibliográficos
Main Authors: Sigurdsson, Martin I., Smith, Albert V., Bjornsson, Hans T., Jonsson, Jon J.
Formato: Artigo
Idioma:Inglês
Publicado: Cold Spring Harbor Laboratory Press 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665777/
https://ncbi.nlm.nih.gov/pubmed/19158364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gr.086181.108
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