Cryptococcal Urease Promotes the Accumulation of Immature Dendritic Cells and a Non-Protective T2 Immune Response within the Lung

Urease, a major virulence factor for Cryptococcus neoformans, promotes lethal meningitis/encephalitis in mice. The effect of urease within the lung, the primary site of most invasive fungal infections, is unknown. An established model of murine infection that utilizes either urease-producing (wt and...

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Hlavní autoři: Osterholzer, John J., Surana, Rishi, Milam, Jami E., Montano, Gerald T., Chen, Gwo-Hsiao, Sonstein, Joanne, Curtis, Jeffrey L., Huffnagle, Gary B., Toews, Galen B., Olszewski, Michal A.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Investigative Pathology 2009
Témata:
Regular Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665753/
https://ncbi.nlm.nih.gov/pubmed/19218345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080673
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