Suppressive Effect of Orthovanadate on Hepatic Stellate Cell Activation and Liver Fibrosis in Rats

Orthovanadate (OV), an inhibitor of protein tyrosine phosphatases, affects various biological processes in a cell-type-specific manner. In this study, we investigated the effect of OV on hepatic stellate cells (HSCs). When primary rat HSCs were cultured in the presence of 10% serum, they spontaneous...

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Autors principals: Nishikawa, Yuji, Ohi, Naoto, Yagisawa, Akiko, Doi, Yuko, Yamamoto, Yohei, Yoshida, Masayuki, Tokairin, Takuo, Yoshioka, Toshiaki, Omori, Yasufumi, Enomoto, Katsuhiko
Format: Artigo
Idioma:Inglês
Publicat: American Society for Investigative Pathology 2009
Matèries:
Regular Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665748/
https://ncbi.nlm.nih.gov/pubmed/19164509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2353/ajpath.2009.080261
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