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Use of soluble peptide–DR4 tetramers to detect synovial T cells specific for cartilage antigens in patients with rheumatoid arthritis

Considerable evidence indicates that CD4(+) T cells are important in the pathogenesis of rheumatoid arthritis (RA), but the antigens recognized by these T cells in the joints of patients remain unclear. Previous studies have suggested that type II collagen (CII) and human cartilage gp39 (HCgp39) are...

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Detalhes bibliográficos
Main Authors: Kotzin, Brian L., Falta, Michael T., Crawford, Frances, Rosloniec, Edward F., Bill, Jerry, Marrack, Philippa, Kappler, John
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2000
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC26656/
https://ncbi.nlm.nih.gov/pubmed/10618411
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