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Mitochondrial DNA level, but not active replicase, is essential for Caenorhabditis elegans development
A number of studies showed that the development and the lifespan of Caenorhabditis elegans is dependent on mitochondrial function. In this study, we addressed the role of mitochondrial DNA levels and mtDNA maintenance in development of C. elegans by analyzing deletion mutants for mitochondrial polym...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2665216/ https://ncbi.nlm.nih.gov/pubmed/19181702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp018 |
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