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Molecular dissection of translation termination mechanism identifies two new critical regions in eRF1

Translation termination in eukaryotes is completed by two interacting factors eRF1 and eRF3. In Saccharomyces cerevisiae, these proteins are encoded by the genes SUP45 and SUP35, respectively. The eRF1 protein interacts directly with the stop codon at the ribosomal A-site, whereas eRF3—a GTPase prot...

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Detalhes bibliográficos
Main Authors: Hatin, Isabelle, Fabret, Celine, Rousset, Jean-Pierre, Namy, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2009
Assuntos:
RNA
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665212/
https://ncbi.nlm.nih.gov/pubmed/19174561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp012
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