Fibrillar amyloid-β burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease

Fibrillar amyloid-beta (Aβ) is found in the brains of many cognitively normal older people. Whether or not this reflects a predisposition to Alzheimer's disease (AD) is unknown. We used Pittsburgh Compound B (PiB) PET to characterize the relationship between fibrillar Aβ burden and this predisp...

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Main Authors: Reiman, Eric M., Chen, Kewei, Liu, Xiaofen, Bandy, Daniel, Yu, Meixiang, Lee, Wendy, Ayutyanont, Napatkamon, Keppler, Jennifer, Reeder, Stephanie A., Langbaum, Jessica B. S., Alexander, Gene E., Klunk, William E., Mathis, Chester A., Price, Julie C., Aizenstein, Howard J., DeKosky, Steven T., Caselli, Richard J.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2009
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665196/
https://ncbi.nlm.nih.gov/pubmed/19346482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900345106
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