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An unstable head-rod junction may promote folding into the compact off-state conformation of regulated myosins
The N-terminal region of myosin’s rod-like subfragment 2 (S2) joins the two heads of this dimeric molecule and is key to its function. Previously, a crystal structure of this predominantly coiled-coil region was determined for a short fragment (51 residues, plus leucine zipper) of the scallop striat...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2007
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2665131/ https://ncbi.nlm.nih.gov/pubmed/18155233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2007.11.071 |
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