Presenilin 1 Affects Focal Adhesion Site Formation and Cell Force Generation via c-Src Transcriptional and Posttranslational Regulation

Presenilin 1 and 2 (PS) are critical components of the γ-secretase complex that cleaves type I transmembrane proteins within their transmembrane domains. This process leads to release of proteolytically processed products from cellular membranes and plays an essential role in signal transduction or...

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Detalhes bibliográficos
Main Authors: Waschbüsch, Dieter, Born, Simone, Niediek, Verena, Kirchgessner, Norbert, Tamboli, Irfan Y., Walter, Jochen, Merkel, Rudolf, Hoffmann, Bernd
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2009
Assuntos:
Molecular Basis of Cell and Developmental Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665068/
https://ncbi.nlm.nih.gov/pubmed/19176482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M806825200
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