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CCR6 Regulation of the Actin Cytoskeleton Orchestrates Human Beta Defensin-2- and CCL20-mediated Restitution of Colonic Epithelial Cells

Intestinal inflammation is exacerbated by defects in the epithelial barrier and subsequent infiltration of microbes and toxins into the underlying mucosa. Production of chemokines and antimicrobial peptides by an intact epithelium provide the first line of defense against invading organisms. In addi...

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Hlavní autoři: Vongsa, Rebecca A., Zimmerman, Noah P., Dwinell, Michael B.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2009
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2665058/
https://ncbi.nlm.nih.gov/pubmed/19233848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M805289200
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