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Estimating Odds Ratios in Genome Scans: An Approximate Conditional Likelihood Approach
In modern whole-genome scans, the use of stringent thresholds to control the genome-wide testing error distorts the estimation process, producing estimated effect sizes that may be on average far greater in magnitude than the true effect sizes. We introduce a method, based on the estimate of genetic...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Human Genetics
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2665019/ https://ncbi.nlm.nih.gov/pubmed/18423522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajhg.2008.03.002 |
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