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Differential response of primary tumor versus lymphatic metastasis to VEGFR-2 and -3 kinase inhibitors cediranib and vandetanib

Blood vessels are required for a tumor to grow and functional lymphatic vessels are required for it to disseminate to lymph nodes. In an attempt to eradicate both the primary tumor and its lymphatic metastasis, we targeted both blood and lymphatic vessels using two different vascular endothelial gro...

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Bibliographische Detailangaben
Hauptverfasser: Padera, Timothy P., Kuo, Angera H., Hoshida, Tohru, Liao, Shan, Lobo, Jennifer, Kozak, Kevin R., Fukumura, Dai, Jain, Rakesh K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2008
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664998/
https://ncbi.nlm.nih.gov/pubmed/18687659
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-0182
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