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The adhesion molecule L1 regulates transendothelial migration and trafficking of dendritic cells

The adhesion molecule L1, which is extensively characterized in the nervous system, is also expressed in dendritic cells (DCs), but its function there has remained elusive. To address this issue, we ablated L1 expression in DCs of conditional knockout mice. L1-deficient DCs were impaired in adhesion...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Maddaluno, Luigi, Verbrugge, Sue Ellen, Martinoli, Chiara, Matteoli, Gianluca, Chiavelli, Andrea, Zeng, Yiping, Williams, Elizabeth D., Rescigno, Maria, Cavallaro, Ugo
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664975/
https://ncbi.nlm.nih.gov/pubmed/19273627
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20081211
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