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Identification of a Motif in the Carboxyl Terminus of CXCR2 That Is Involved in Adaptin 2 Binding and Receptor Internalization

Agonist treatment of cells expressing the chemokine receptor, CXCR2, induces receptor phosphorylation and internalization through a dynamin-dependent mechanism. In the present study, we demonstrate that a carboxyl terminus-truncated mutant of CXCR2 (331T), which no longer undergoes agonist-induced p...

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Detalhes bibliográficos
Main Authors: Fan, Guo-Huang, Yang, Wei, Wang, Xue-Jie, Qian, Qinghua, Richmond, Ann
Formato: Artigo
Idioma:Inglês
Publicado em: 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664867/
https://ncbi.nlm.nih.gov/pubmed/11170396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi001661b
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