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Evaluating cell-surface expression and measuring activation of mammalian odorant receptors in heterologous cells

A fundamental question in olfaction is which odorant receptors (ORs) are activated by a given odorant. A major roadblock to investigate odorant-OR relationship in mammals has been an inability to express ORs in heterologous cells suitable for screening active ligands for ORs. The discovery of the re...

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Detalhes bibliográficos
Principais autores: Zhuang, Hanyi, Matsunami, Hiroaki
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664838/
https://ncbi.nlm.nih.gov/pubmed/18772867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nprot.2008.120
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