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Crystallization and preliminary crystallographic analysis of fragaceatoxin C, a pore-forming toxin from the sea anemone Actinia fragacea

Sea anemones produce water-soluble toxins that have the ability to interact with cell membranes and form pores within them. The mechanism of pore formation is based on an initial binding step followed by oligomerization and membrane insertion. Although the final structure of the pore remains unclear...

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Main Authors: Mechaly, A. E., Bellomio, A., Morante, K., González-Mañas, J. M., Guérin, D. M. A.
Format: Artigo
Jezik:Inglês
Izdano: International Union of Crystallography 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664759/
https://ncbi.nlm.nih.gov/pubmed/19342779
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S1744309109007064
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