Effect of Simvastatin on Cognitive Functioning in Children With Neurofibromatosis Type 1: A Randomized Controlled Trial

CONTEXT: Neurofibromatosis type 1 (NF1) is among the most common genetic disorders that cause learning disabilities. Recently, it was shown that statin-mediated inhibition of 3-hydroxy-3-methylglutaryl coenzyme A reductase restores the cognitive deficits in an NF1 mouse model. OBJECTIVE: To determin...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Krab, Lianne C., de Goede-Bolder, Arja, Aarsen, Femke K., Pluijm, Saskia M. F., Bouman, Marlies J., van der Geest, Jos N., Lequin, Maarten, Catsman, Coriene E., Arts, Willem Frans M., Kushner, Steven A., Silva, Alcino J., de Zeeuw, Chris I., Moll, Henriëtte A., Elgersma, Ype
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2008
Aiheet:
Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664742/
https://ncbi.nlm.nih.gov/pubmed/18632543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1001/jama.300.3.287
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia