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NFATc3-dependent loss of I(to) gradient across the left ventricular wall during chronic β adrenergic stimulation
In heart, pore-forming Kv4 α channel subunits underlie the K(+) transient outward current (I(to)). Expression of Kv4 is greater in left ventricular epicardial (EPI) than in endocardial (ENDO) cells, resulting in larger I(to) in EPI than in ENDO cells. In adult ventricular myocytes, the transcription...
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| Main Authors: | , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2664558/ https://ncbi.nlm.nih.gov/pubmed/19027024 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2008.10.016 |
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