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Regression of human pancreatic tumor xenografts in mice after a single systemic injection of recombinant vaccinia virus GLV-1h68

Oncolytic virotherapy of tumors has shown promising results in both preclinical and clinical studies. Here, we investigated the therapeutic efficacy of a replication-competent vaccinia virus, GLV-1h68, against human pancreatic carcinomas in cell cultures and in nude mice. We found that GLV-1h68 was...

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Detalles Bibliográficos
Main Authors: Yu, Yong A., Galanis, Charles, Woo, Yanghee, Chen, Nanhai, Zhang, Qian, Fong, Yuman, Szalay, Aladar A.
Formato: Artigo
Idioma:Inglês
Publicado: 2009
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664310/
https://ncbi.nlm.nih.gov/pubmed/19139123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-08-0533
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