Support for the involvement of large copy number variants in the pathogenesis of schizophrenia

We investigated the involvement of rare (<1%) copy number variants (CNVs) in 471 cases of schizophrenia and 2792 controls that had been genotyped using the Affymetrix GeneChip® 500K Mapping Array. Large CNVs >1 Mb were 2.26 times more common in cases (P = 0.00027), with the effect coming mostl...

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Bibliographic Details
Main Authors: Kirov, George, Grozeva, Detelina, Norton, Nadine, Ivanov, Dobril, Mantripragada, Kiran K., Holmans, Peter, Craddock, Nick, Owen, Michael J., O'Donovan, Michael C.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2009
Subjects:
Association Studies Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664144/
https://ncbi.nlm.nih.gov/pubmed/19181681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddp043
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