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Toxicity and Intraocular Properties of a Novel Long-Acting Anti-Proliferative and Anti-Angiogenic Compound IMS2186

PURPOSE: To investigate the intraocular properties and toxicity of IMS2186, a small molecule developed as an anti-choroidal neovascularization (anti-CNV) drug. MATERIALS AND METHODS: Cellular toxicity and mechanism of action was tested on cell lines in vitro. Intraocular studies used rabbits for dru...

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Main Authors: Falkenstein, Iryna A., Cheng, Lingyun, Wong-Staal, Flossie, Tammewar, Ajay M., Barron, Erin C., Silva, Gabriel A., Li, Qi-Xiang, Yu, Dehua, Hysell, Michelle, Liu, Guohong, Ke, Ning, Macdonald, James E., Freeman, William R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664073/
https://ncbi.nlm.nih.gov/pubmed/18600493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/02713680802226582
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