TNF/iNOS-producing dendritic cells are the necessary evil of lethal influenza virus infection

Respiratory infection with highly pathogenic influenza A viruses is characterized by the exuberant production of cytokines and chemokines and the enhanced recruitment of innate inflammatory cells. Here, we show that challenging mice with virulent influenza A viruses, including currently circulating...

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Bibliographic Details
Main Authors: Aldridge, Jerry R., Moseley, Carson E., Boltz, David A., Negovetich, Nicholas J., Reynolds, Cory, Franks, John, Brown, Scott A., Doherty, Peter C., Webster, Robert G., Thomas, Paul G.
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664048/
https://ncbi.nlm.nih.gov/pubmed/19279209
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900655106
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