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Genome-wide discovery of functional transcription factor binding sites by comparative genomics: The case of Stat3

The identification of direct targets of transcription factors is a key problem in the study of gene regulatory networks. However, the use of high throughput experimental methods, such as ChIP-chip and ChIP-sequencing, is limited by their high cost and strong dependence on cellular type and context....

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Detalhes bibliográficos
Main Authors: Vallania, Francesco, Schiavone, Davide, Dewilde, Sarah, Pupo, Emanuela, Garbay, Serge, Calogero, Raffaele, Pontoglio, Marco, Provero, Paolo, Poli, Valeria
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2664024/
https://ncbi.nlm.nih.gov/pubmed/19282476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0900473106
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