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Direct and specific inactivation of protein tyrosine kinases in the Src and FGFR families by reversible cysteine oxidation

Accumulating evidence suggests that protein tyrosine phosphorylation-based signaling pathways are under the regulation of reactive oxygen species. Although protein tyrosine phosphatases are directly regulated by reversible oxidation, it is not clear whether protein tyrosine kinases (PTKs) are also d...

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Bibliographic Details
Main Authors: Kemble, David J., Sun, Gongqin
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663993/
https://ncbi.nlm.nih.gov/pubmed/19273857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0806117106
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