Integrated Functional, Gene Expression and Genomic Analysis for the Identification of Cancer Targets

The majority of new drug approvals for cancer are based on existing therapeutic targets. One approach to the identification of novel targets is to perform high-throughput RNA interference (RNAi) cellular viability screens. We describe a novel approach combining RNAi screening in multiple cell lines...

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Detalhes bibliográficos
Main Authors: Iorns, Elizabeth, Lord, Christopher J., Grigoriadis, Anita, McDonald, Sarah, Fenwick, Kerry, MacKay, Alan, Mein, Charles A., Natrajan, Rachael, Savage, Kay, Tamber, Narinder, Reis-Filho, Jorge S., Turner, Nicholas C., Ashworth, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2009
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663812/
https://ncbi.nlm.nih.gov/pubmed/19357772
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005120
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