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Intranasal Delivery of Cholera Toxin Induces Th17-Dominated T-Cell Response to Bystander Antigens

Cholera toxin (CT) is a potent vaccine adjuvant, which promotes mucosal immunity to protein antigen given by nasal route. It has been suggested that CT promotes T helper type 2 (Th2) response and suppresses Th1 response. We here report the induction of Th17-dominated responses in mice by intranasal...

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Bibliografiske detaljer
Main Authors: Lee, Jee-Boong, Jang, Ji-Eun, Song, Man Ki, Chang, Jun
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663811/
https://ncbi.nlm.nih.gov/pubmed/19360100
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005190
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