Large scale replication and meta-analysis of variants on chromosome 4q25 associated with atrial fibrillation

AIMS: A recent genome-wide association study identified a haplotype block on chromosome 4q25 associated with atrial fibrillation (AF). We sought to replicate this association in four independent cohorts. METHODS AND RESULTS: The Framingham Heart Study and Rotterdam Study are community-based longitud...

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Autori principali: Kääb, Stefan, Darbar, Dawood, van Noord, Charlotte, Dupuis, Josée, Pfeufer, Arne, Newton-Cheh, Christopher, Schnabel, Renate, Makino, Seiko, Sinner, Moritz F., Kannankeril, Prince J., Beckmann, Britt M., Choudry, Subbarao, Donahue, Brian S., Heeringa, Jan, Perz, Siegfried, Lunetta, Kathryn L., Larson, Martin G., Levy, Daniel, MacRae, Calum A., Ruskin, Jeremy N., Wacker, Annette, Schömig, Albert, Wichmann, H.-Erich, Steinbeck, Gerhard, Meitinger, Thomas, Uitterlinden, André G., Witteman, Jacqueline C.M., Roden, Dan M., Benjamin, Emelia J., Ellinor, Patrick T.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Oxford University Press 2009
Soggetti:
Clinical Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663727/
https://ncbi.nlm.nih.gov/pubmed/19141561
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/eurheartj/ehn578
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