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Longitudinal Changes of mtDNA A3243G Mutation Load and Level of Functioning in MELAS

Mitochondrial encephalopathy, lactic acidosis, and stroke-like episodes (MELAS), one of the most common mitochondrial multisystemic diseases, is most commonly associated with an A-to-G transition at nucleotide position 3243 (A3243G) in mitochondrial DNA. We studied 34 individuals harboring the A3243...

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Main Authors: Mehrazin, Mahsa, Shanske, Sara, Kaufmann, Petra, Wei, Ying, Coku, Jorida, Engelstad, Kristin, Naini, Ali, De Vivo, Darryl C, DiMauro, Salvatore
格式: Artigo
語言:Inglês
出版: 2009
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663596/
https://ncbi.nlm.nih.gov/pubmed/19253345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.a.32703
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