Fluorine-19 NMR Chemical Shift Probes Molecular Binding to Lipid Membranes

The binding of amphiphilic molecules to lipid bilayers is followed by (19)F NMR using chemical shift and line shape differences between the solution and membrane-tethered states of –CF(3) and –CHF(2) groups. A chemical shift separation of 1.6 ppm combined with a high natural abundance and high sensi...

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Main Authors: Chekmenev, Eduard Y., Chow, Siu-Kei, Tofan, Daniel, Weitekamp, Daniel P., Ross, Brian D., Bhattacharya, Pratip
Format: Artigo
Sprog:Inglês
Udgivet: 2008
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663341/
https://ncbi.nlm.nih.gov/pubmed/18422359
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jp800646k
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