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Multiple Mechanisms Contribute to the Robust Rapid Gamma Interferon Response by CD8(+) T Cells during Listeria monocytogenes Infection

A subset of CD8(+) T cells can rapidly secrete gamma interferon (IFN-γ) in an antigen-independent and interleukin-12 (IL-12)- and IL-18-dependent manner within 16 h of infection with the intracellular bacterial pathogen Listeria monocytogenes. This rapid IFN-γ response is robust enough to be detecte...

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Main Authors: Bou Ghanem, Elsa N., McElroy, Denise S., D'Orazio, Sarah E. F.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2009
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663144/
https://ncbi.nlm.nih.gov/pubmed/19179413
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.01207-08
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