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Use of a Surface Plasmon Resonance Method To Investigate Antibiotic and Plasma Protein Interactions

The pharmacologic effect of an antibiotic is directly related to its unbound concentration at the site of infection. Most commercial antibiotics have been selected in part for their low propensity to interact with serum proteins. These nonspecific interactions are classically evaluated by measuring...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Banères-Roquet, Françoise, Gualtieri, Maxime, Villain-Guillot, Philippe, Pugnière, Martine, Leonetti, Jean-Paul
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663126/
https://ncbi.nlm.nih.gov/pubmed/19164148
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00971-08
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