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Roles of NF-κB Activation and Peroxisome Proliferator-Activated Receptor Gamma Inhibition in the Effect of Rifampin on Inducible Nitric Oxide Synthase Transcription in Human Lung Epithelial Cells

Rifampin (rifampicin), an important antibiotic agent and a major drug used for the treatment of tuberculosis, exerts immunomodulatory effects. Previous studies have found that rifampin increases inducible nitric oxide (NO) synthase (iNOS) expression and NO production. The present study investigated...

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Autors principals: Yuhas, Yael, Berent, Eva, Cohen, Regev, Ashkenazi, Shai
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology (ASM) 2009
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663117/
https://ncbi.nlm.nih.gov/pubmed/19114679
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00961-08
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