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Genetic Analysis of Factors Affecting Susceptibility of Bacillus subtilis to Daptomycin

Daptomycin is the first of a new class of cyclic lipopeptide antibiotics used against multidrug-resistant, gram-positive pathogens. The proposed mechanism of action involves disruption of the functional integrity of the bacterial membrane in a Ca(2+)-dependent manner. We have used transcriptional pr...

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Detalhes bibliográficos
Main Authors: Hachmann, Anna-Barbara, Angert, Esther R., Helmann, John D.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663116/
https://ncbi.nlm.nih.gov/pubmed/19164152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01329-08
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