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Population Pharmacokinetics of High-Dose, Prolonged-Infusion Cefepime in Adult Critically Ill Patients with Ventilator-Associated Pneumonia

A population pharmacokinetic model of cefepime was constructed from data from adult critical care patients with ventilator-associated pneumonia (VAP). A total of 32 patients treated with high-dose cefepime, 2 g every 8 h (3-h infusion) or a renal function-adjusted equivalent dose, were randomized in...

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Bibliografiske detaljer
Main Authors: Nicasio, Anthony M., Ariano, Robert E., Zelenitsky, Sheryl A., Kim, Aryun, Crandon, Jared L., Kuti, Joseph L., Nicolau, David P.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2009
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663089/
https://ncbi.nlm.nih.gov/pubmed/19188394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01141-08
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