Hereditary pancreatitis caused by mutation induced misfolding of human cationic trypsinogen - a novel disease mechanism

We investigated the biochemical properties and cellular expression of the c.346C>T (p.R116C) human cationic trypsinogen (PRSS1) mutant, which we identified in a German family with autosomal dominant hereditary pancreatitis. This mutation leads to an unpaired Cys residue with the potential to inte...

Ful tanımlama

Kaydedildi:
Detaylı Bibliyografya
Asıl Yazarlar: Kereszturi, Éva, Szmola, Richárd, Kukor, Zoltán, Simon, Peter, Weiss, Frank Ulrich, Lerch, Markus M., Sahin-Tóth, Miklós
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2663013/
https://ncbi.nlm.nih.gov/pubmed/19191323
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/humu.20853
Etiketler: Etiketle
Etiket eklenmemiş, İlk siz ekleyin!

Benzer Materyaller