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Rapid Membrane Disruption by a Perforin-Like Protein Facilitates Parasite Exit from Host Cells

Perforin-like proteins are expressed by many bacterial and protozoan pathogens, yet little is known about their function or mode of action. Here we describe TgPLP1, a secreted perforin-like protein of the intracellular protozoan pathogen Toxoplasma gondii that displays structural features necessary...

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Bibliografski detalji
Glavni autori: Kafsack, Björn F.C., Pena, Janethe D. O., Coppens, Isabelle, Ravindran, Sandeep, Boothroyd, John C., Carruthers, Vern B.
Format: Artigo
Jezik:Inglês
Izdano: 2008
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662845/
https://ncbi.nlm.nih.gov/pubmed/19095897
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1165740
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