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Rapid Membrane Disruption by a Perforin-Like Protein Facilitates Parasite Exit from Host Cells
Perforin-like proteins are expressed by many bacterial and protozoan pathogens, yet little is known about their function or mode of action. Here we describe TgPLP1, a secreted perforin-like protein of the intracellular protozoan pathogen Toxoplasma gondii that displays structural features necessary...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2662845/ https://ncbi.nlm.nih.gov/pubmed/19095897 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1165740 |
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