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A novel method for producing target cells and assessing cytotoxic T lymphocyte activity in outbred hosts

BACKGROUND: Cytotoxic T lymphocytes play a crucial role in the immunological control of microbial infections and in the design of vaccines and immunotherapies. Measurement of cytotoxic T lymphocyte activity requires that the test antigen is presented by target cells having the same or compatible cla...

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Detalhes bibliográficos
Main Authors: Bonci, Francesca, Zabogli, Elisa, Conti, Francesca, Merico, Antonio, Freer, Giulia, Bendinelli, Mauro, Pistello, Mauro
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662824/
https://ncbi.nlm.nih.gov/pubmed/19284578
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1472-6750-9-18
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