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Ascorbic acid pre-treated quartz stimulates TNF-α release in RAW 264.7 murine macrophages through ROS production and membrane lipid peroxidation

BACKGROUND: Inhalation of crystalline silica induces a pulmonary fibrotic degeneration called silicosis caused by the inability of alveolar macrophages to dissolve the crystalline structure of phagocytosed quartz particles. Ascorbic acid is capable of partially dissolving quartz crystals, leading to...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Scarfì, Sonia, Magnone, Mirko, Ferraris, Chiara, Pozzolini, Marina, Benvenuto, Federica, Benatti, Umberto, Giovine, Marco
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BioMed Central 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662810/
https://ncbi.nlm.nih.gov/pubmed/19298665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-10-25
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