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Mechanism of Copper Activated Transcription: Activation of AP-1, and the JNK/SAPK and p38 Signal Transduction Pathways

Copper is an essential metal that is able to produce reactive oxygen species and induce intracellular oxidative stress. Several studies have examined the effects of excessive copper and oxidative stress in various organisms and tissues, but few address the molecular mechanisms by which copper affect...

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Detalhes bibliográficos
Principais autores: Mattie, Michael D., McElwee, Matthew K., Freedman, Jonathan H.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662727/
https://ncbi.nlm.nih.gov/pubmed/18793645
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2008.08.080
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