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A Radiation-Derived Gene Expression Signature Predicts Clinical Outcome for Breast Cancer Patients

Activation of the DNA damage response pathway is a hallmark for early tumorigenesis, while loss of pathway activity is associated with disease progression. Thus we hypothesized that a gene expression signature associated with the DNA damage response may serve as a prognostic signature for outcome in...

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Détails bibliographiques
Auteurs principaux: Piening, Brian D., Wang, Pei, Subramanian, Aravind, Paulovich, Amanda G.
Format: Artigo
Langue:Inglês
Publié: 2009
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662705/
https://ncbi.nlm.nih.gov/pubmed/19267539
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1667/RR1223.1
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