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SHIP is required for a functional hematopoietic stem cell niche
SH2-domain-containing inositol 5′-phosphatase-1 (SHIP) deficiency significantly increases the number of hematopoietic stem cells (HSCs) present in the bone marrow (BM). However, the reconstitution capacity of these HSCs is severely impaired, suggesting that SHIP expression might be an intrinsic requ...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2662639/ https://ncbi.nlm.nih.gov/pubmed/19074735 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2008-02-138008 |
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