Use of Salsalate to Target Inflammation in the Treatment of Insulin Resistance and Type 2 Diabetes

Objectives: Chronic subacute inflammation is implicated in the pathogenesis of insulin resistance and type 2 diabetes. Salicylates were shown years ago to lower glucose and more recently to inhibit NF‐κB activity. Salsalate, a prodrug form of salicylate, has seen extensive clinical use and has a fav...

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Autors principals: Goldfine, Allison B., Silver, Robert, Aldhahi, Waleed, Cai, Dongsheng, Tatro, Elizabeth, Lee, Jongsoon, Shoelson, Steven E.
Format: Artigo
Idioma:Inglês
Publicat: Blackwell Publishing Inc 2008
Matèries:
Research Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662587/
https://ncbi.nlm.nih.gov/pubmed/19337387
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1752-8062.2008.00026.x
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