Characterization of Rv3868, an Essential Hypothetical Protein of the ESX-1 Secretion System in Mycobacterium tuberculosis

Rv3868, a conserved hypothetical protein of the ESAT-6 secretion system of Mycobacterium tuberculosis, is essential for the secretion of at least four virulence factors. Each protein chain is ∼63 kDa and assembles into a hexamer. Limited proteolysis demonstrates that it consists of two domains joine...

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Main Authors: Luthra, Amit, Mahmood, Anjum, Arora, Ashish, Ramachandran, Ravishankar
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2008
Teme:
Enzyme Catalysis and Regulation
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2662308/
https://ncbi.nlm.nih.gov/pubmed/18974091
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M807144200
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